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Home Archives for Toxicity

Public Health Alert

Quinine & Quinidine: Toxic Adulterants Found in Illicit Street Drugs

June 24, 2022

Quinine and its naturally occurring stereoisomer quinidine are natural alkaloids found in the bark of the cinchona tree, originally from South America. Today, quinine and quinidine are individually synthesized for…
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Public Health Alert

Tramadol: A Toxic Adulterant Found in Illicit Street Drugs

May 28, 2021

Tramadol is a synthetic opioid analgesic approved in 1995 by the United States Food and Drug Administration (FDA) for moderate to moderately severe pain. Its mechanism of action involves opioid…
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Public Health Alert

Dipyrone (Metamizole): A Toxic Adulterant Found in Illicit Street Drugs

May 25, 2021

Dipyrone is a non-opioid analgesic with antipyretic activity, which was developed by the German company Hoechst AG in 1920 with mass production starting in 1922. It is a pro-drug, which…
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Public Health Alert

Phenacetin: A Toxic Adulterant Found in Illicit Street Drugs

April 20, 2021

Phenacetin, a pain-relieving and fever-reducing drug, was discovered as an analgesic in 1887. It was one of the first synthetic fever reducers on the market and one of the first…
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