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Home Archives for Postmortem

Public Health Alert

Bromazolam Prevalence Surging Across the United States Driven In Part by Increasing Detections Alongside Fentanyl

June 15, 2022

Bromazolam first emerged in the recreational drug supply in 2016 (Europe) and 2019 (United States). Bromazolam was first synthesized during medicinal drug development in the 1970s but never approved for…
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Public Health Alert

Synthetic Stimulant Market Rapidly Changing as N,N-Dimethylpentylone Replaces Eutylone in Drug Supply Typically Sold as “Ecstasy” or “Molly”

April 20, 2022

In 2020 and 2021, the substituted cathinone eutylone was the most commonly encountered synthetic stimulant to appear in forensic casework, despite the drug being considered federally scheduled as an isomer…
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Public Health Alert

Etodesnitazene — New Synthetic Opioid Identified During Forensic Death Investigations in the United States and Canada

December 14, 2021

Etodesnitazene is a new synthetic opioid bearing structural resemblance to etonitazene, a synthetic opioid that is nationally and internationally controlled. Etodesnitazene is dissimilar in structure to synthetic opioids typically encountered…
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Public Health Alert

New Synthetic Opioid Protonitazene Increasing in Prevalence as “Nitazenes” Gain Traction Across the United States and Canada

December 10, 2021

Protonitazene is a new, potent synthetic opioid bearing structural resemblance to etonitazene, a synthetic opioid that is nationally and internationally controlled. Protonitazene is dissimilar in structure to synthetic opioids typically…
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Public Health Alert

New High Potency Synthetic Opioid N-Pyrrolidino Etonitazene (Etonitazepyne) Linked to Overdoses Across United States

June 17, 2021

N-Pyrrolidino etonitazene (etonitazepyne) is a new high potency synthetic opioid bearing structural resemblance to etonitazene, a synthetic opioid that is nationally and internationally controlled. N-Pyrrolidino etonitazene is dissimilar in structure…
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Public Health Alert

Positivity of New Synthetic Cannabinoid 4F-MDMB-BICA Increasing in U.S. as Prevalence of 5F-MDMB-PICA Wanes

February 8, 2021

4F-MDMB-BICA was first identified in the United States (U.S.) in plant-like material seized by law enforcement in May 2020 and soon after in toxicology casework in July 2020, with concurrent…
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Public Health Alert

Metonitazene Begins Proliferation as Newest Synthetic Opioid Among Latest Cycle of Non-Fentanyl Related Drugs

January 25, 2021

Metonitazene is a potent synthetic opioid bearing structural resemblance to etonitazene, a synthetic opioid that is nationally and internationally controlled. Metonitazene is dissimilar in structure to other synthetic opioids typically…
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Public Health Alert

Fluorofentanyl Identified in Forensic Casework as Wave of Fentanyl-Related Substances Appears in the United States

December 3, 2020

Fluorofentanyl was identified as early as 2016 in the U.S. and Europe, but overall detections remained low until recent months. Positivity of para-fluorofentanyl began increasing in Q3 2020 and within…
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Public Health Alert

Prevalence of Synthetic Cannabinoid MDMB-4en-PINACA Continues to Increase in the United States and Internationally

October 15, 2020

MDMB-4en-PINACA was first identified in toxicology casework in the United States in September 2019; however, its emergence dates back earlier to seized drug testing from Europe in June 2018. MDMB-4en-PINACA…
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Public Health Alert

The Rise of Brorphine — A Potent New Synthetic Opioid Identified in the Midwestern United States

July 27, 2020

Brorphine is a potent synthetic opioid with structural resemblance to fentanyl and its analogues. However, brorphine is not controlled in the U.S. under core-structure scheduling of fentanyl related substances. Recent…
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Alex J. Krotulski, PhD
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Mandi L.A. Mohr, MSFS, D-ABFT-FT
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Sara E. Walton, BS
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Executive Director

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