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Public Health Alert

Fluorofentanyl Identified in Forensic Casework as Wave of Fentanyl-Related Substances Appears in the United States

December 3, 2020

Fluorofentanyl was identified as early as 2016 in the U.S. and Europe, but overall detections remained low until recent months. Positivity of para-fluorofentanyl began increasing in Q3 2020 and within…
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Public Health Alert

Updated Trend Reporting for the NPS Benzodiazepine Clonazolam Based on Data-Mining for 8-Aminoclonazolam

November 5, 2020

Clonazolam (also called clonitazolam) first emerged in the recreational drug supply in 2014 (Europe) and 2016 (United States). Like many NPS, clonazolam was first synthesized during drug development in 1971…
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Public Health Alert

Prevalence of Synthetic Cannabinoid MDMB-4en-PINACA Continues to Increase in the United States and Internationally

October 15, 2020

MDMB-4en-PINACA was first identified in toxicology casework in the United States in September 2019; however, its emergence dates back earlier to seized drug testing from Europe in June 2018. MDMB-4en-PINACA…
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Public Health Alert

The Rise of Brorphine — A Potent New Synthetic Opioid Identified in the Midwestern United States

July 27, 2020

Brorphine is a potent synthetic opioid with structural resemblance to fentanyl and its analogues. However, brorphine is not controlled in the U.S. under core-structure scheduling of fentanyl related substances. Recent…
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