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Public Health Alert

Positivity of New Synthetic Cannabinoid 4F-MDMB-BICA Increasing in U.S. as Prevalence of 5F-MDMB-PICA Wanes

February 8, 2021

4F-MDMB-BICA was first identified in the United States (U.S.) in plant-like material seized by law enforcement in May 2020 and soon after in toxicology casework in July 2020, with concurrent…
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Public Health Alert

Metonitazene Begins Proliferation as Newest Synthetic Opioid Among Latest Cycle of Non-Fentanyl Related Drugs

January 25, 2021

Metonitazene is a potent synthetic opioid bearing structural resemblance to etonitazene, a synthetic opioid that is nationally and internationally controlled. Metonitazene is dissimilar in structure to other synthetic opioids typically…
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Public Health Alert

Fluorofentanyl Identified in Forensic Casework as Wave of Fentanyl-Related Substances Appears in the United States

December 3, 2020

Fluorofentanyl was identified as early as 2016 in the U.S. and Europe, but overall detections remained low until recent months. Positivity of para-fluorofentanyl began increasing in Q3 2020 and within…
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Public Health Alert

Prevalence of Synthetic Cannabinoid MDMB-4en-PINACA Continues to Increase in the United States and Internationally

October 15, 2020

MDMB-4en-PINACA was first identified in toxicology casework in the United States in September 2019; however, its emergence dates back earlier to seized drug testing from Europe in June 2018. MDMB-4en-PINACA…
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