The CFSRE is developing NPS Discovery Toolkits as a consolidation of our program outcomes into a comprehensive new document detailing relevant information about the detection and characterization of a specified NPS. This “toolkit” includes basic drug information, date of first appearance, prevalence, temporal trends, geographical trends, demographics, poly-drug combinations (including with other NPS), metabolism, methods for identification and confirmation, reference concentration ranges, and much more. This report is designed to serve as a one-stop resource for scientists and interested individuals looking for all-inclusive information about a new drug.