Cayman Chemical and NPS Discovery at the Center for Forensic Science Research and Education (CFSRE) have developed new, more appropriate names to address the newly emergent “MDA-19” and its related…
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N-Pyrrolidino etonitazene (etonitazepyne) is a new high potency synthetic opioid bearing structural resemblance to etonitazene, a synthetic opioid that is nationally and internationally controlled. N-Pyrrolidino etonitazene is dissimilar in structure…
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Tramadol is a synthetic opioid analgesic approved in 1995 by the United States Food and Drug Administration (FDA) for moderate to moderately severe pain. Its mechanism of action involves opioid…
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Dipyrone is a non-opioid analgesic with antipyretic activity, which was developed by the German company Hoechst AG in 1920 with mass production starting in 1922. It is a pro-drug, which…
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The objective of this report is to provide guidance in developing an appropriate analytical scope of testing for novel psychoactive substances (NPS) in the United States based on current trends…
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Phenacetin, a pain-relieving and fever-reducing drug, was discovered as an analgesic in 1887. It was one of the first synthetic fever reducers on the market and one of the first…
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4F-MDMB-BICA was first identified in the United States (U.S.) in plant-like material seized by law enforcement in May 2020 and soon after in toxicology casework in July 2020, with concurrent…
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Metonitazene is a potent synthetic opioid bearing structural resemblance to etonitazene, a synthetic opioid that is nationally and internationally controlled. Metonitazene is dissimilar in structure to other synthetic opioids typically…
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Fluorofentanyl was identified as early as 2016 in the U.S. and Europe, but overall detections remained low until recent months. Positivity of para-fluorofentanyl began increasing in Q3 2020 and within…
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Clonazolam (also called clonitazolam) first emerged in the recreational drug supply in 2014 (Europe) and 2016 (United States). Like many NPS, clonazolam was first synthesized during drug development in 1971…
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